');--success-svg-icon:url('data:image/svg+xml;utf8,');--info-svg-icon:url('data:image/svg+xml;utf8,');--chevron-svg-icon:url('data:image/svg+xml;utf8,');--checkbox-svg-icon:url('data:image/svg+xml;utf8,');--radiobutton-svg-icon:url('data:image/svg+xml;utf8,');--show-password-svg-icon:url('data:image/svg+xml;utf8,');--hide-password-svg-icon:url('data:image/svg+xml;utf8,');--error-svg-icon-color:var(--red-500);--success-svg-icon-color:var(--emerald-700);--info-svg-icon-color:var(--sky-500);--chevron-svg-icon-color:var(--grey-900);--checkbox-svg-icon-color:var(--grey-900);--radiobutton-svg-icon-color:var(--grey-900);--show-password-svg-icon-color:var(--grey-900);--hide-password-svg-icon-color:var(--grey-900);--bde-woo-notices__icon-size:16px;--bde-woo-notices__padding:24px;--bde-woo-notices__border-radius:4px;--bde-woo-notices__error-background:var(--red-50);--bde-woo-notices__error-text:var(--red-500);--bde-woo-notices__error-link-text:var(--red-500);--bde-woo-notices__error-link-text-hover:var(--red-500);--bde-woo-notices__info-background:var(--sky-100);--bde-woo-notices__info-text:var(--sky-500);--bde-woo-notices__info-link-text:var(--sky-500);--bde-woo-notices__info-link-text-hover:var(--sky-500);--bde-woo-notices__success-background:var(--emerald-100);--bde-woo-notices__success-text:var(--emerald-700);--bde-woo-notices__success-link-text:var(--emerald-700);--bde-woo-notices__success-link-text-hover:var(--emerald-700);--bde-woo-sale-badge__border-radius:2px;--bde-woo-sale-badge__padding:4px 8px;--bde-woo-ratings__star-color:var(--yellow-500);--bde-woo-ratings__star-size:18px;--bde-woo-ratings__filled-star-svg:url('data:image/svg+xml;utf8,');--bde-woo-ratings__empty-star-svg:url('data:image/svg+xml;utf8,');--bde-woo-product-images__border-radius:4px;--bde-woo-product-images__border-width:0px;--bde-woo-product-images__border-color:var(--grey-300);--bde-woo-wrappers__background-color:var(--white);--bde-woo-wrappers__border-radius:4px;--bde-woo-wrappers__border-color:var(--grey-300);--bde-woo-wrappers__border-width:1px;--bde-woo-wrappers__shadow:rgba(0,0,0,.05) 0 1px 3px,rgba(0,0,0,.05) 0 1px 2px;--bde-woo-tables__header-color:var(--grey-100);--bde-woo-tables__background-color:var(--white);--bde-woo-tables__border-radius:4px;--bde-woo-tables__border-width:1px;--bde-woo-widgets__chip-background-color:transparent;--bde-woo-widgets__chip-background-color-hover:var(--indigo-50);--bde-woo-widgets__chip-text-color:inherit;--bde-woo-widgets__handle-border-color:var(--grey-300);--bde-woo-widgets__handle-background-color:var(--white);--bde-woo-widgets__handle-background-color-hover:var(--white);--bde-woo-widgets__handle-shadow:rgba(0,0,0,.05) 0 1px 3px,rgba(0,0,0,.05) 0 1px 2px;--bde-woo-widgets__handle-shadow-hover:var(--grey-300) 0 0 4px;--bde-woo-widgets__remove-item-from-cart-color:var(--grey-450);--bde-woo-select2__active-item-background-color:var(--indigo-50);--bde-woo-gallery__zoom-icon-shadow:rgba(0,0,0,.05) 0 1px 3px,rgba(0,0,0,.05) 0 1px 2px;--bde-woo-payment-box-background-color:var(--grey-100);--bde-woo-payment-box-border-color:var(--grey-200);--bde-woo-payment-box-border-width:1px;--bde-woo-quicklook-button-icon:url(/wp-content/uploads/breakdance/css/icons/eye.svg);--bde-woo-quicklook-button-background-color:none;--bde-woo-quicklook-button-icon-size:20px;--bde-woo-quicklook-button-backdrop-color:rgba(0,0,0,.15);--bde-woo-quicklook-button-backdrop-opacity:.7;--bde-woo-quicklook-modal-background-color:var(--white);--bde-woo-quicklook-overlay-color:rgba(0,0,0,.7);--bde-woo-quicklook-close-button-size:2em;--bde-woo-quicklook-arrow-size:1em;--bde-woo-quicklook-arrow-color:var(--white);--bde-woo-swatch-space-between-options:10px;--bde-woo-swatch-padding:7px;--bde-woo-swatch-color-width:30px;--bde-woo-swatch-color-height:30px;--bde-woo-swatch-border:1px solid var(--grey-200);--bde-woo-swatch-border-color-hover:var(--grey-400);--bde-woo-swatch-shadow:none;--bde-woo-swatch-shadow-hover:none;--bde-woo-swatch-background:var(--white);--bde-woo-swatch-background-hover:var(--grey-50);--bde-woo-swatch-color-padding:2px;--bde-woo-swatch-tooltip-color:var(--white);--bde-woo-swatch-tooltip-background:var(--grey-900);--bde-woo-swatch-tooltip-padding:7px;--bde-woo-swatch-space-after-label:8px;--bde-woo-responsive__stack:row}:root{--bde-links-color:var(--bde-brand-primary-color);--bde-links-color-hover:var(--bde-brand-primary-color-hover);--bde-button-primary-background-color:var(--bde-brand-primary-color);--bde-button-primary-background-color-hover:var(--bde-brand-primary-color-hover);--bde-button-secondary-border-color:var(--bde-brand-primary-color);--bde-button-secondary-border-color-hover:var(--bde-brand-primary-color);--bde-button-secondary-text-color:var(--bde-brand-primary-color);--bde-button-secondary-background-color-hover:var(--bde-brand-primary-color);--bde-button-text-text-color:var(--bde-links-color);--bde-button-text-text-color-hover:var(--bde-links-color-hover);--bde-button-font-size:var(--bde-body-font-size);--bde-form-font-size:var(--bde-body-font-size);--bde-form-input-border-top-left-radius:var(--bde-form-input-border-radius);--bde-form-input-border-top-right-radius:var(--bde-form-input-border-radius);--bde-form-input-border-bottom-left-radius:var(--bde-form-input-border-radius);--bde-form-input-border-bottom-right-radius:var(--bde-form-input-border-radius);--bde-form-input-border-top:var(--bde-form-input-border-width) solid var(--bde-form-input-border-color);--bde-form-input-border-right:var(--bde-form-input-border-width) solid var(--bde-form-input-border-color);--bde-form-input-border-bottom:var(--bde-form-input-border-width) solid var(--bde-form-input-border-color);--bde-form-input-border-left:var(--bde-form-input-border-width) solid var(--bde-form-input-border-color);--bde-form-label-color:var(--bde-headings-color);--bde-form-input-focused-border-color:var(--bde-brand-primary-color);--bde-form-input-focused-shadow:var(--bde-brand-primary-color) 0 0 2px;--bde-form-checkbox-selected-color:var(--bde-brand-primary-color);--bde-z-index-lightbox:1100;--bde-z-index-popup:1050;--bde-z-index-modal:1000;--bde-z-index-modal-backdrop:calc(var(--bde-z-index-modal) - 1);--bde-z-index-high:300;--bde-z-index-medium:200;--bde-z-index-low:100;--bde-z-index-sticky:10;--bde-z-index-minicart:var(--bde-z-index-modal);--bde-z-index-minicart-backdrop:var(--bde-z-index-modal-backdrop);--bde-z-index-menu-dropdown:var(--bde-z-index-modal);--bde-z-index-menu-mobile:var(--bde-z-index-modal);--bde-z-index-menu-backdrop:var(--bde-z-index-modal-backdrop);--bde-z-index-search-fullscreen:var(--bde-z-index-modal);--bde-z-index-back-to-top:var(--bde-z-index-high);--bde-z-index-scroll-progress:var(--bde-z-index-high);--bde-z-index-header-sticky:var(--bde-z-index-medium);--bde-z-index-header-overlay:calc(var(--bde-z-index-header-sticky) - 1);--bde-z-index-social-share-buttons:var(--bde-z-index-low);--bde-woo-base-text-color:var(--bde-body-text-color);--bde-woo-base-headings-color:var(--bde-headings-color);--bde-woo-base-primary-color:var(--bde-brand-primary-color);--bde-woo-base-primary-color-hover:var(--bde-brand-primary-color-hover);--bde-woo-base-extra-small-gaps:calc(var(--bde-woo-base-small-gaps)/var(--bde-woo-base-ratio));--bde-woo-base-small-gaps:calc(var(--bde-woo-base-space)/var(--bde-woo-base-ratio));--bde-woo-base-standard-gaps:var(--bde-woo-base-space);--bde-woo-base-medium-gaps:calc(var(--bde-woo-base-space)*var(--bde-woo-base-ratio));--bde-woo-base-big-gaps:calc(var(--bde-woo-base-medium-gaps)*var(--bde-woo-base-ratio));--bde-woo-base-large-gaps:calc(var(--bde-woo-base-big-gaps)*var(--bde-woo-base-ratio));--bde-woo-base-extra-large-gaps:calc(var(--bde-woo-base-large-gaps)*var(--bde-woo-base-ratio));--bde-woo-typography-ratio:var(--bde-font-size-ratio);--bde-woo-typography__size-small:calc(var(--bde-woo-typography__size-standard)/var(--bde-woo-typography-ratio));--bde-woo-typography__size-small-font-family:var(--bde-body-font-family);--bde-woo-typography__size-standard:var(--bde-body-font-size);--bde-woo-typography__size-standard-font-family:var(--bde-body-font-family);--bde-woo-typography__size-medium:calc(var(--bde-woo-typography__size-standard)*var(--bde-woo-typography-ratio));--bde-woo-typography__size-medium-font-family:var(--bde-heading-font-family);--bde-woo-typography__size-large:calc(var(--bde-woo-typography__size-medium)*var(--bde-woo-typography-ratio));--bde-woo-typography__size-large-font-family:var(--bde-heading-font-family);--bde-woo-typography__size-extra-large:calc(var(--bde-woo-typography__size-large)*var(--bde-woo-typography-ratio));--bde-woo-typography__size-extra-large-font-family:var(--bde-heading-font-family);--bde-woo-buttons-and-links__text-link-color:var(--bde-woo-base-primary-color);--bde-woo-buttons-and-links__text-link-color-hover:var(--bde-woo-base-primary-color-hover);--bde-woo-buttons-and-links__nav-link-color:var(--bde-woo-base-text-color);--bde-woo-buttons-and-links__nav-link-color-hover:var(--bde-woo-base-text-on-primary-color);--bde-woo-buttons-and-links__nav-link-color-active:var(--bde-woo-base-primary-color);--bde-woo-forms__spacing-after-label:var(--bde-form-after-label);--bde-woo-forms__spacing-between-fields:var(--bde-form-gap);--bde-woo-forms__spacing-between-columns:var(--bde-woo-base-extra-large-gaps);--bde-woo-forms__labels-color:var(--bde-form-label-color);--bde-woo-forms__inputs-background-color:var(--bde-form-input-background-color);--bde-woo-forms__inputs-text-color:var(--bde-form-text-color);--bde-woo-forms__inputs-placeholder-color:var(--bde-form-input-placeholder-color);--bde-woo-forms__inputs-border-color:var(--bde-form-input-border-color);--bde-woo-forms__inputs-border-width:var(--bde-form-input-border-width);--bde-woo-forms__inputs-border-radius:var(--bde-form-input-border-top-left-radius) var(--bde-form-input-border-top-right-radius) var(--bde-form-input-border-bottom-right-radius) var(--bde-form-input-border-bottom-left-radius);--bde-woo-forms__inputs-background-color-focused:var(--bde-form-input-focused-background-color);--bde-woo-forms__inputs-border-color-focused:var(--bde-form-input-focused-border-color);--bde-woo-forms__inputs-shadow-focused:var(--bde-form-input-focused-shadow);--bde-woo-forms__inputs-shadow:var(--bde-form-input-input-shadow);--bde-woo-forms__inputs-select2-hover-item:var(--bde-woo-base-primary-color);--bde-woo-forms__labels-required-color:var(--bde-form-label-required-color);--bde-woo-forms__labels-required-size:var(--bde-form-label-required-size);--bde-woo-forms__labels-required-nudge-x:var(--bde-form-label-required-nudge-x);--bde-woo-forms__labels-required-nudge-y:var(--bde-form-label-required-nudge-y);--bde-woo-tables__border-color:var(--bde-woo-base-border-color);--bde-woo-sale-badge__background-color:var(--bde-woo-base-primary-color);--bde-woo-sale-badge__text-color:var(--bde-woo-base-text-on-primary-color);--bde-woo-sale-badge__font-weight:var(--bde-woo-typography-font-weight-heavy);--bde-woo-sale-badge__font-size:var(--bde-woo-typography__size-standard);--bde-woo-widgets__chip-text-color-hover:var(--bde-woo-buttons-and-links__text-link-color);--bde-woo-widgets__handle-border-color-hover:var(--bde-woo-base-primary-color);--bde-woo-notices__padding-left:calc(var(--bde-woo-notices__padding) + var(--bde-woo-notices__icon-size) + (var(--bde-woo-notices__icon-size)/2));--bde-woo-quicklook-button-text-color:var(--bde-button-primary-text-color);--bde-woo-quicklook-button-background-color-hover:var(--bde-woo-quicklook-button-background-color);--bde-woo-quicklook-button-icon-spacing:var(--bde-woo-base-standard-gaps);--bde-woo-quicklook-close-button-color:var(--bde-woo-base-headings-color);--bde-woo-quicklook-arrow-color-hover:var(--bde-woo-quicklook-arrow-color);--bde-woo-quicklook-arrow-background-color:var(--bde-brand-primary-color);--bde-woo-quicklook-arrow-background-color-hover:var(--bde-woo-quicklook-arrow-background-color);--bde-woo-swatch-space-between-items:var(--bde-woo-base-medium-gaps);--bde-woo-swatch-background-selected:var(--bde-woo-swatch-background-hover);--bde-woo-swatch-border-color-selected:var(--bde-woo-swatch-border-color-hover);--bde-woo-swatch-shadow-selected:var(--bde-woo-swatch-shadow-hover);--bde-woo-swatch-color-background:var(--bde-woo-swatch-background)}.breakdance .button-atom{display:inline-flex;align-items:center;justify-content:center;vertical-align:middle;appearance:none;box-sizing:border-box;margin:0;border:0;padding:0;background-color:transparent;font-size:var(--bde-button-font-size);line-height:var(--bde-button-line-height);transform:translate(0,0);max-width:100%;width:var(--bde-button-width)}.breakdance .button-atom--custom{text-align:center;font-weight:var(--bde-button-font-weight);text-decoration:none;padding:var(--bde-button-padding-base);border-radius:var(--bde-button-border-radius);border-width:var(--bde-button-border-width);border-style:solid;border-color:transparent;overflow:hidden}.breakdance .button-atom--custom{color:var(--bde-button-custom-text-color);background:var(--bde-button-custom-background-color);border-color:var(--bde-button-custom-border-color)}.breakdance *,.breakdance *:before,.breakdance *:after{box-sizing:border-box}.breakdance img{max-width:100%;height:auto}.breakdance 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De ontwikkeling van verslaving, waaronder afhankelijkheid van THC, wordt beïnvloed door zowel genetische als omgevingsfactoren. Terwijl omgevingsfactoren zoals sociale omstandigheden en stress een belangrijke rol spelen, toont steeds meer onderzoek aan dat genetische aanleg ook een significante bijdrage levert. Dit artikel onderzoekt de rol van genetica in THC-verslaving, de genetische markers die zijn geïdentificeerd, en hoe genetische predispositie van invloed kan zijn op de behandeling van verslaving.
Wetenschappers schatten dat 40-75% van de kwetsbaarheid voor verslaving erfelijk is, afhankelijk van het type middel. Onderzoek heeft honderden genen geïdentificeerd die verband houden met verslavingsgevoeligheid. Deze genetische factoren beïnvloeden de manier waarop het beloningssysteem van de hersenen reageert op middelen zoals THC, alcohol en nicotine. Dit betekent dat sommige mensen door hun genetische opmaak een hoger risico lopen om afhankelijk te worden van THC.
Naast de bekende genen zoals COMT, dat betrokken is bij de afbraak van dopamine, spelen ook andere genen een rol bij verslaving. Het DRD2-gen, dat de dopamine D2-receptor codeert, is direct gekoppeld aan de gevoeligheid voor verslavingen door verstoring van het beloningssysteem. Andere belangrijke genen zijn het OPRM1-gen, dat codeert voor de opioïdreceptor en betrokken is bij het beloningssysteem, en het CHRNA5-CHRNA3-CHRNB4-gencluster, dat in verband wordt gebracht met nicotineverslaving. Samen beïnvloeden deze genen hoe mensen reageren op psychoactieve stoffen, inclusief THC.
Recent onderzoek heeft specifiek gekeken naar cannabisgebruik en genetica. Nederlandse wetenschappers hebben 35 genen geïdentificeerd die geassocieerd zijn met cannabisgebruik. Het meest significante gen dat naar voren kwam is CADM2, dat eerder werd gelinkt aan alcoholgebruik en risicovol gedrag. Mensen met bepaalde genetische profielen kunnen gevoeliger zijn voor de effecten van THC en lopen een hoger risico op afhankelijkheid, vooral wanneer ze op jonge leeftijd beginnen met cannabisgebruik.
Verslaving komt vaak voor in families, wat suggereert dat genetische factoren een belangrijke rol spelen. Onderzoek naar families met een geschiedenis van middelenmisbruik, inclusief THC, toont aan dat kinderen van ouders die afhankelijk zijn van drugs een verhoogd risico hebben om zelf afhankelijk te worden van middelen. Genetische kwetsbaarheid wordt vaak versterkt door omgevingsfactoren, zoals een sociale omgeving waarin drugsgebruik genormaliseerd is.
De erkenning dat genetica een rol speelt in verslavingsgevoeligheid opent de deur naar gepersonaliseerde behandelmethoden. Mensen met een genetische aanleg voor verslaving kunnen baat hebben bij behandelingen die zich richten op hun specifieke genetische kwetsbaarheden. Zo kunnen medicijnen die de dopaminebalans herstellen, zoals naltrexon, effectiever zijn voor mensen met een genetische variant van de dopamine D2-receptor. Evenzo kunnen mensen met een genetische variatie in de µ-opioïdreceptor (OPRM1) baat hebben bij een aangepaste behandeling.
Met de opkomst van genetische testen kan in de toekomst een gepersonaliseerde benadering van verslavingszorg mogelijk worden. Dit kan leiden tot behandelingen die specifiek zijn afgestemd op iemands genetisch profiel, wat de effectiviteit van therapieën kan vergroten. Onderzoek naar genetische varianten heeft al aangetoond dat ze de uitkomsten van behandelingen zoals naltrexon en ondansetron bij alcoholverslaving kunnen beïnvloeden. Deze inzichten kunnen in de toekomst worden toegepast om effectievere behandelingen voor THC-verslaving te ontwikkelen.
Genetische predispositie speelt een belangrijke rol in het risico op THC-verslaving. Terwijl omgevingsfactoren zoals sociale invloed en stress cruciaal blijven, tonen studies aan dat genetica voor een groot deel verantwoordelijk is voor de kwetsbaarheid voor verslaving. Mensen met een genetische aanleg lopen een verhoogd risico om afhankelijk te worden van THC, wat implicaties heeft voor de behandeling van deze groep. Door genetica op te nemen in behandelmethoden, kunnen gepersonaliseerde zorgstrategieën worden ontwikkeld, wat kan leiden tot betere behandelresultaten voor mensen die worstelen met verslaving.
Wie is Green Grown en waar staan wij voor?
Bij Green Grown geloven we in de kracht van cannabis om een gezonde en bewuste levensstijl te ondersteunen, met een focus op kwaliteit, transparantie en duurzaamheid. Wij helpen mensen bij het ontdekken van de voordelen van CBD, zonder de risico’s die gepaard gaan met THC-gebruik.
Onze missie is om THC-vrije cannabis te integreren in een bewuste en gezonde levensstijl. Sluit je aan bij onze gemeenschap en help de perceptie van cannabis te transformeren.
Cannabis bloemen kunnen online niet verkocht worden. Je kan dus geen cannabis bloemen terugvinden in onze online winkel maar vindt er wel tal van kwalitatieve CBD-producten zoals CBD-olie, CBD voor huisdieren, CBD-cosmetica en meer.
Indien je op zoek bent naar cannabis bloemen raden wij jou aan een bezoekje te brengen aan een van onze 6 conceptstores of naar een van onze cannabis verdelers in jouw buurt te gaan. Meer informatie over onze conceptstores.